Science is difficult and slow no matter who you are. The hours are long, and the glorious ‘aha’ days come only very infrequently. You have to keep believing that if you put in the hours, those days will indeed come! – Bonnie Bassler
You can find bacteria everywhere. They’re invisible to us. I’ve never seen a bacterium, except under a microscope. They’re so small, we don’t see them, but they are everywhere. – Bonnie Bassler
Think about multicellularity on this Earth. Every living thing originally came from bacteria. So, who do you think made up the rules for how to perform collective behaviors? It had to be the bacteria. – Bonnie Bassler
I am lucky because I get to work with the smartest, most creative, and most devoted group of students and postdoctoral fellows imaginable. – Bonnie Bassler
We’ve all been sick; we’re all afraid of infection. I think the easiest application to help people understand what quorum sensing is and why it’s important to study is to tell them that if we could make the bacteria either deaf or mute, we could create new antibiotics. – Bonnie Bassler
Bacteria live in unbelievable mixtures of hundreds or thousands of species. Like on your teeth. There are 600 species of bacteria on your teeth every morning. – Bonnie Bassler
What’s great about bacteria is you have a surprise every day waiting for you because they’re so fast, they grow overnight. – Bonnie Bassler
I realized that lab research was the perfect path for me. It allowed me to spend every day figuring out mysteries/puzzles that have to do with what make us alive. What could be a bigger mystery or puzzle? – Bonnie Bassler
Everybody, as soon as they do a good experiment, their first thought in this lab is, ‘That can’t be right. I must have screwed it up. What did I do wrong?’ And that’s the best kind of scientist because they’re filled with this self-doubt. And if I’m going to be honest, that’s who I am. And it’s what drives me. – Bonnie Bassler
I think being open-minded about what Nature is trying to tell you is the key to being creative and successful. – Bonnie Bassler
Bacteria are single-celled organisms. Bacteria are the model organisms for everything that we know in higher organisms. There are 10 times more bacterial cells in you or on you than human cells. – Bonnie Bassler
It’s incorrect to think of bacteria as these asocial, single cells. They are individual cells, but they act in communities, exactly the way people do. – Bonnie Bassler
When antibiotics became industrially produced following World War II, our quality of life and our longevity improved enormously. No one thought bacteria were going to become resistant. – Bonnie Bassler
All these bacteria that coat our skin and live in our intestines, they fend off bad bacteria. They protect us. And you can’t even digest your food without the bacteria that are in your gut. They have enzymes and proteins that allow you to metabolize foods you eat. – Bonnie Bassler
It’s a manic-depressive life. You run in here, you open your incubator, your experiment makes no sense, you think, ‘I hate this job.’ Then ten minutes later you think, ‘Well, now, maybe I’ll try this or I’ll try that.’ You do it because you know there will be an ‘a-ha!’ day. – Bonnie Bassler
As a kid, I loved doing puzzles, solving riddles, and reading mystery books. I also loved animals and always had pets. – Bonnie Bassler
I went to UC Davis because I wanted to be a vet. It’s a great profession if it’s right for you, but it’s memorizing the bones and the muscles, and I am terrible at stuff like that. Also, there’s a lot of blood and gore involved. – Bonnie Bassler
In my lab, we are always thinking about how cells, bacterial cells, can talk to each other and then organize themselves into enormous groups that function in unison. – Bonnie Bassler
The goal of scientists is you hope that the thing you’re working on is bigger than the thing you’re pipetting into that tube at that moment. – Bonnie Bassler
I think the easiest application to help people understand what quorum sensing is and why it’s important to study is to tell them that if we could make the bacteria either deaf or mute, we could create new antibiotics. – Bonnie Bassler
I remember the day we found the gene for the inter-species signaling molecule like it was yesterday. We got the gene, and we plugged it into a database. And we immediately saw that this gene was in an amazing number of species of bacteria. It was a huge moment of realization. – Bonnie Bassler
Most bacteria aren’t bad. We breathe and eat and ingest gobs of bacteria every single moment of our lives. Our food is covered in bacteria. And you’re breathing in bacteria all the time, and you mostly don’t get sick. – Bonnie Bassler
When antibiotics first came out, nobody could have imagined we’d have the resistance problem we face today. We didn’t give bacteria credit for being able to change and adapt so fast. – Bonnie Bassler
