Hundreds of people are undergoing gene therapy today. There are no known neurological issues. – Liz Parrish
We have a battery of tests planned at regular intervals including DNA methylation analysis, gene expression profile changes, telomere length (both TAT and QTRAP measured) and various other metrics that will highlight positive changes to aging biomarkers. – Liz Parrish
I am happy to be patient zero. It is for the world, for the sick children and sick old people. My life has been good. I understand the risks but I research how people die and I am happy to say that today I do not know how I will die now. Tomorrow or in the long future I was up for a change. – Liz Parrish
Exercise and eat healthy foods in moderation. I am a vegetarian but that is a personal choice. – Liz Parrish
Aging is one of the most visual diseases on the planet and includes things that we all know like wrinkles and grey hair, but also brain atrophy, muscle wasting and organ damage. – Liz Parrish
Gene therapy technology is much like computing technology. We had to build the super computer which cost $8 million in 1960. Now everyone has technologies that work predictably and at a cost the average person can afford. – Liz Parrish
Work by Maria Blasco, Calvin Harley, Michael Fossel, Woodring Wright and Shay and Ronald Depinho in particular are of interest but there are literally thousands of articles relating to telomerase, telomeres and the biology behind it. – Liz Parrish
As lifespan increases fertility rates go down all over the world. Humans will create better technology and space travel will increase. These are all good signs for the future. – Liz Parrish
Epigenetics is very important. We are keeping a close eye on iPS cells and other genetic methods of reprogramming the epigenome. – Liz Parrish
I agree Maria Blasco has achieved amazing things with telomerase induction and we are hopeful this will translate to the human model. – Liz Parrish
You have little to no response to AAV the first time your body sees it. If you used the same vector twice you would want to bump up immunosuppression. I believe there will be many new ways to deliver genes in the future as well. – Liz Parrish
We are looking at gene therapies to Reverse Atherosclerosis, Regenerate muscles and tissue, Improve cell signaling, Clear misfolded Proteins, Rejuvenate the immune System, Clear Senescent Cells, and Treat Monogenic Diseases. – Liz Parrish
The biotech game is quickly changing. The people must demand their use of these treatments. – Liz Parrish
But do remember that the most important risk factor for cancer is growing older. Most cancers occur in people over the age of 65. – Liz Parrish
I was awake for the therapy, it was documented by a film crew. I am proud to have taken part of helping millions of people even if it has bad results. – Liz Parrish
BioViva is trying to help improve human health and wellbeing, and alleviate suffering. We are not trying to determine who should live or die. Everyone has a right to life without suffering. – Liz Parrish